Best Description: Pneumonia Oral Rehydration Therapy [2023]

Pneumonia Oral Rehydration Therapy. Reduction of orthostatic intolerance by oral rehydration in patients with myalgic encephalomyelitis/chronic fatigue syndrome. All answers & details are below.

Pneumonia Oral Rehydration Therapy

We recommend that you carefully read this article about Pneumonia Oral Rehydration Therapy, which is very detailed and explained in the best way. Pneumonia etc. in your environment. If there is someone who has a disease, you should definitely go to the doctor without wasting time.

Oral rehydration therapy (ORT) has been considered one of the treatments in medicine for many years. A method of treatment used to prevent and treat dehydration caused by many diseases, including those that cause diarrhea.

Pneumonia is a respiratory infection. However, it typically does not cause dangerous fluid loss through diarrhea or vomiting, which are the primary indications for ORT. Therefore, oral rehydration therapy is not the primary treatment option for pneumonia.

Pneumonia is defined as a type of infection that affects the lungs and is usually caused by bacteria, viruses or fungi. Pneumonia Oral Rehydration Therapy depends on many underlying causes. In many cases, pneumonia can be treated with antibiotics if it is caused by bacteria. If the pneumonia is of viral origin, antiviral drugs are used. In severe cases, intravenous drug administration may be required. Of course, hospitalization may be required for supportive care.

Oral rehydration solutions (ORS) are generally used to replenish fluids and electrolytes lost due to conditions such as diarrhea and vomiting. Adequate hydration is also very important for people with pneumonia. Pneumonia Oral Rehydration Therapy continues.

Reduction of orthostatic intolerance by oral rehydration in patients with myalgic encephalomyelitis/chronic fatigue syndrome

Pneumonia Oral Rehydration Therapy / Intravenous central BV expansion with isotonic saline is widely and effectively used to reduce OI, regardless of etiology. But it is not without complications when used for a long time. Common forms of oral hydration do not provide similar benefits. Strangely, a specific isotonic oral rehydration solution (ORS WHO formula) that takes advantage of the combined transport of glucose and sodium has been shown to efficiently rehydrate cholera patients. This suggests its ability to increase central BV competing with intravenous fluids.

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The circulatory effects of saline or ORS-BV expansion are poorly understood. It is recommended to investigate the neurovascular physiology of fluid loading during orthostatic loading in ME/CFS patients with POTS or LMWH and compare the results with healthy controls. Equal volumes of ORS are said to be probably superior, if not inferior, to intravenous saline infusion in increasing intravascular and interstitial fluid volume, as well as improving orthostatic tolerance. Pneumonia Oral Rehydration Therapy is very important when necessary.

• STUDY TYPE: interventional

• ENROLLMENT (PROBABLY): 45

• PHASE: stage 1

Contacts And Locations

This section contains the contact details of those conducting the study and information about where this study is being conducted.

Places Of Study

• United States

Eligibility Criteria

Researchers look for people who fit a specific description, called selection criteria. Some examples of these criteria are a person’s general health or previous treatments. Pneumonia Oral Rehydration Therapy continues.

Eligibility Criteria

• ELIGIBLE AGE: 15 years to 29 years (child, adult)

• ACCEPTS HEALTHY VOLUNTEERS: No

• ELIGIBLE GENDERS: All

DESCRIPTION

Inclusion Criteria:

• Both female and male participants will be studied
• Age 15-29
• All subjects must meet myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) criteria, including 15 with neural mediated syncope (NMS) and 15 with postural tachycardia syndrome (POTS).
• ME/CFS patients with NMS are cases with episodic symptoms of orthostatic intolerance (OI) associated with 3 or more episodes of sudden loss of consciousness and postural tone within the last year (simple fainting).
• ME/CFS patients with POTS will have chronic day-to-day OI symptoms for at least 3 months. POTS is confirmed by duplicating these symptoms using a tilt table test
• Healthy volunteers are accepted and disease free

Exclusion criteria:

• All subjects have a normal physical examination and are free of all systemic diseases
• no subjects will take neurally active or vasoactive drugs. All previous medications are discontinued for at least 2 weeks.

Curriculum

This section provides details of the curriculum, including study design and measurement of study content. https://ichgcp.net/de/clinical-trials-registry/NCT02854683

How is the study structured?

• Pneumonia Oral Rehydration Therapy is a very important issue. All answers below.

DESIGN DETAILS

• Main purpose : treatment
• Allocation : Random
• Intervention model : crossover task
• Masking : None (Open Label)

WEAPONS AND INTERVENTIONS

Participant group / arm	Intervention / Treatment
Experimental: Normal salineSubjects receive 1 liter of intravenous physiological saline over 1 hour and on a second day subjects drink a total of 1 liter of ORS solution orally over 20 minutes.	Drug: Normal saline1 liter of intravenous saline is given over 1 hourOther names:NSS
Experimental: Oral rehydration solutionSubjects receive 1 liter of intravenous physiological saline over 1 hour and on a second day subjects drink a total of 1 liter of ORS solution orally over 20 minutes.	Dietary supplement: Oral rehydration solution1 liter ORS oral solutionOther names:ORS

What does the study measure?

• Pneumonia Oral Rehydration Therapy continues. All answers below.

PRIMARY OUTCOME MEASURES

result measure

Measure description

To test whether 1-liter volumes of an intravenous or oral rehydration solution increase total blood volume and cardiac output, thereby comparably improving the orthostatic intolerance thresholdTime window: 1 week

We measure total blood volume, cardiorespiratory properties, plasma osmolarity, and electrolytes before and after 1 hour after the completion of an intravenous infusion of normal saline. Hematocrit is measured every 10 minutes for changes in blood volume. On a second day, we measure total blood volume, cardiorespiratory properties, plasma osmolarity, and electrolytes before and after 1 hour after ingestion of 1 liter of oral rehydration solution. Hematocrit is measured every 10 minutes for changes in blood volume.

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